hrp0095t20 | Section | ESPE2022

Sensitivity to thyroid hormones and cardiometabolic risk in euthyroid obese children: a cross-sectional study.

Tropeano Angelo , Corica Domenico , Lorenza Curatola Selenia , Li Pomi Alessandra , Alibrandi Angela , Pepe Giorgia , Aversa Tommaso , Wasniewska Malgorzata

Background: The typical biochemical phenotype related to obesity, that is high serum thyrotropin (TSH) within normal range, low/normal free thyroxine (FT4) and increased free triiodothyronine (FT3) levels, can be interpreted as a resistance to thyroid hormones. It is unclear the role played by thyroid hormones in the pathogenesis of metabolic derangement associated with obesity.Aim: To investigate the association between...